Overview of Selected Chemical Compounds and Intermediates

Overview of Selected Chemical Compounds and Intermediates

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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This can be an impurity relevant to bortezomib, a proteasome inhibitor Utilized in the remedy of a number of myeloma. Its synthesis or research is crucial for making sure the purity and basic safety from the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor while in the synthesis of abiraterone acetate, a drug used in the treatment of prostate most cancers by inhibiting androgen generation.
Imatinib Intermediate (CAS NO. 152460-10-one): A important compound inside the synthesis of imatinib, a drug that targets particular types of most cancers, which includes Serious myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Utilized in the synthesis of docetaxel, a chemotherapy medication that treats various cancers for instance breast, lung, and prostate cancer.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): They're intermediates during the synthesis of gemcitabine, an anti-cancer drug. Their review is vital for optimizing the manufacturing system and making sure substantial purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is utilized to deal with breast most cancers, and these intermediates are linked to its creation.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist Employed in the therapy of breast most cancers. Many intermediates help in the synthesis of this drug.
Paclitaxel Side Chain Acid 6-diaMine (CAS NO. 949023-16-9): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug effective in dealing with cancers for instance ovarian, breast, and lung most cancers.
3. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug used in the therapy of colorectal cancer and modest cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-eighty two-9): This compound is associated with the synthesis of adamantane derivatives, which have a variety of apps, together with antiviral Homes.
Vildagliptin Intermediates: Utilized in the manufacture of vildagliptin, an oral drug for kind 2 diabetes that inhibits the enzyme DPP-four to control blood sugar concentrations.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is involved with the synthesis of varied gluconic acid derivatives, that happen to be Utilized in foodstuff, Cb 7598 pharmaceutical, and industrial apps.
Canagliflozin Intermediate 2: A precursor inside the synthesis of canagliflozin, a medication utilised to handle sort 2 diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).